BayBioMS - Targeted Metabolomics
To monitor specific differences between sample sets, targeted metabolomics has the aim to accurately quantify molecules of interest. Mass spectrometric quantitation has the big advantage of high sensitivity and selectivity. Since the ionization of the analytes strongly depends on their chemical structures and the co-eluting matrix, proper calibration methods are needed to obtain the desired accuracy, precision and linearity of the quantitation method. Please click on the different calibration methods to learn more about advantages and disadvantages of each respective method.
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· Stable Isotope Dilution Assay